Web of Science - Scientists have discovered the Achilles heel of HIV: an amino acid sequence as the amino acid sequence 421-433 of this number frasers centrepoint homes is on HIV (AIDS virus) membrane glycoprotein GP120 was found. Outer membrane glycoprotein of HIV envelope protein major, HIV through which adsorbed on the CD4 receptor, which receptors are present in human T4 lymphocytes, and the body's immune system as the most important target for T4 lymphocytes, swallowed frasers centrepoint homes a lot of damage T4 lymphocytes, thereby undermining the human immune system, and ultimately the collapse of the immune system, the body due to the loss of resistance to various diseases and disease and death. It is worth mentioning that, HIV itself does not cause any disease, so scientists call this virus called "human immunodeficiency virus." There is no effective vaccine against HIV.
Dr. Paul (Sudhir Paul, Ph.D.) from the Texas Medical College (UT Medical School), said: "HIV requires at least a stable area to attack human cells once this region changes, HIV can not infect cells Similarly,. It does not want the region to promote the body's immune system starts. So, HIV uses the same affiliated regional cells to inhibit human B lymphocytes, while the main function of B cells is the production of a variety of antibodies. immunologist these region frasers centrepoint homes is called a super antigens Thus, HIV after a series of reactions, from the start of the single-stranded RNA HIV eventually frasers centrepoint homes form a cyclic double-stranded DNA molecule that, under the guidance of a virus-encoded integrase, as the provirus into the host DNA in this case the synthetic DNA of cells is controlled when the formation of daughter cells, the provirus also replicated. "
Paul, where the research team used an enzyme to produce antibodies, also known as antibody enzyme. This antibody enzyme capable of accurately attack this number is the amino acid sequence 421-433 of. Paul said: "Because the antibody enzyme can recognize a wide variety of HIV virus in the world, so do not worry be problematic new HIV variants our next goal of this experiment is to be applied to the human body, in order. confirm our previous inferences. "Such frasers centrepoint homes antibodies can be permanently enzyme inhibition of viral replication, only one such antibody molecules capable of inhibiting the enzyme thousands of virus particles, and the antibody can inhibit the ordinary one virus particles, and they Unable to stop the HIV virus replication activity powerful particle.
This antibody capture enzyme mainly in the crowd carrying the HIV virus, which is part of many people suffering from autoimmune disease lupus, a small amount is also collected from the crowd did not carry the HIV virus. A graduate frasers centrepoint homes from the University of Texas, said they found that lupus patient's immune system is damaged body can produce this amino acid sequence of the antibody enzyme. After a long period of evolution, the human body can manufacture many are called endogenous retroviral sequences of the virus. In lupus patient's body, such retroviral frasers centrepoint homes sequences massive viral replication, so they will produce this antibody frasers centrepoint homes enzyme. After the impact in the course of decades, not a small part of the body carrying the HIV virus, an enzyme will produce frasers centrepoint homes such antibodies. Another expert said that this enzyme can neutralize HIV-infected human cells. He also said that the new findings will make a significant contribution in the fight against the HIV virus, and now they face a difficult problem is how to be able to convert it to a vaccine or a fungicide to prevent the spread of HIV through sexual frasers centrepoint homes intercourse .
| Print | Comments | Forum | blog | Papers by: Related News "AIDS": innate immunity against HIV study specific genes from the United States, said edit specific genes make people frasers centrepoint homes immune to AIDS in a university doctoral conjunction of Nanjing users infected with HIV U.S. studies have shown that the use of a laser to destroy the AIDS or HIV virus Watch detailed analysis of the birth of the "natural" paper BMJ: touch with reality UNAIDS should be closed PNAS: inhibition of a specific frasers centrepoint homes enzyme activity capable of blocking HIV replication latest survey: most prospects for an HIV vaccine scientists feel ... one week Top News MOST: 17 State Key Laboratory has been "bottom out", "science": Tsinghua frasers centrepoint homes University graduate "rule" America PhD doctoral frasers centrepoint homes Yun experiments cited explosion injured will face amputation Wan Gang said the scientist alone era is over "Running Fan" To go to Tianjin seeking assistance sue the Ministry of Education and the CCTV "natural": newly discovered fossil "amputation" stumble Darwin's "stump" American frasers centrepoint homes The group of experts set up a thorough investigation of China's research capacity frasers centrepoint homes Tsinghua Academy graduation streaker two boys want to be more inclusive of Tsinghua University
Dr. Paul (Sudhir Paul, Ph.D.) from the Texas Medical College (UT Medical School), said: "HIV requires at least a stable area to attack human cells once this region changes, HIV can not infect cells Similarly,. It does not want the region to promote the body's immune system starts. So, HIV uses the same affiliated regional cells to inhibit human B lymphocytes, while the main function of B cells is the production of a variety of antibodies. immunologist these region frasers centrepoint homes is called a super antigens Thus, HIV after a series of reactions, from the start of the single-stranded RNA HIV eventually frasers centrepoint homes form a cyclic double-stranded DNA molecule that, under the guidance of a virus-encoded integrase, as the provirus into the host DNA in this case the synthetic DNA of cells is controlled when the formation of daughter cells, the provirus also replicated. "
Paul, where the research team used an enzyme to produce antibodies, also known as antibody enzyme. This antibody enzyme capable of accurately attack this number is the amino acid sequence 421-433 of. Paul said: "Because the antibody enzyme can recognize a wide variety of HIV virus in the world, so do not worry be problematic new HIV variants our next goal of this experiment is to be applied to the human body, in order. confirm our previous inferences. "Such frasers centrepoint homes antibodies can be permanently enzyme inhibition of viral replication, only one such antibody molecules capable of inhibiting the enzyme thousands of virus particles, and the antibody can inhibit the ordinary one virus particles, and they Unable to stop the HIV virus replication activity powerful particle.
This antibody capture enzyme mainly in the crowd carrying the HIV virus, which is part of many people suffering from autoimmune disease lupus, a small amount is also collected from the crowd did not carry the HIV virus. A graduate frasers centrepoint homes from the University of Texas, said they found that lupus patient's immune system is damaged body can produce this amino acid sequence of the antibody enzyme. After a long period of evolution, the human body can manufacture many are called endogenous retroviral sequences of the virus. In lupus patient's body, such retroviral frasers centrepoint homes sequences massive viral replication, so they will produce this antibody frasers centrepoint homes enzyme. After the impact in the course of decades, not a small part of the body carrying the HIV virus, an enzyme will produce frasers centrepoint homes such antibodies. Another expert said that this enzyme can neutralize HIV-infected human cells. He also said that the new findings will make a significant contribution in the fight against the HIV virus, and now they face a difficult problem is how to be able to convert it to a vaccine or a fungicide to prevent the spread of HIV through sexual frasers centrepoint homes intercourse .
| Print | Comments | Forum | blog | Papers by: Related News "AIDS": innate immunity against HIV study specific genes from the United States, said edit specific genes make people frasers centrepoint homes immune to AIDS in a university doctoral conjunction of Nanjing users infected with HIV U.S. studies have shown that the use of a laser to destroy the AIDS or HIV virus Watch detailed analysis of the birth of the "natural" paper BMJ: touch with reality UNAIDS should be closed PNAS: inhibition of a specific frasers centrepoint homes enzyme activity capable of blocking HIV replication latest survey: most prospects for an HIV vaccine scientists feel ... one week Top News MOST: 17 State Key Laboratory has been "bottom out", "science": Tsinghua frasers centrepoint homes University graduate "rule" America PhD doctoral frasers centrepoint homes Yun experiments cited explosion injured will face amputation Wan Gang said the scientist alone era is over "Running Fan" To go to Tianjin seeking assistance sue the Ministry of Education and the CCTV "natural": newly discovered fossil "amputation" stumble Darwin's "stump" American frasers centrepoint homes The group of experts set up a thorough investigation of China's research capacity frasers centrepoint homes Tsinghua Academy graduation streaker two boys want to be more inclusive of Tsinghua University
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